Travelers to Prague Urged to Get Hepatitis A Vaccination Amid Rising Infections

Published on September 6, 2025

Travelers heading to Prague and surrounding areas in Czechia are being advised to get vaccinated against Hepatitis A (HAV) due to a significant increase in infections. According to reports from the Czechia State Institute of Health, the country has experienced a multi-month outbreak that has now led to 1,348 confirmed cases of Hepatitis A, including 15 deaths in 2025 alone. As Prague remains one of the most visited cities in Czechia, this health alert is especially important for tourists planning to visit the city.

The Hepatitis A virus primarily affects the liver and is caused by consuming food or water contaminated with fecal matter. While travelers can generally avoid the virus by following basic hygiene practices, the recent uptick in cases highlights the need for proactive measures, such as vaccination.

As of September 2025, the majority of cases have been reported in Prague (436 cases), Central Bohemia (202), and the Moravian-Silesian Region (118). Health officials suggest that the outbreak is largely affecting vulnerable populations, including individuals who are homeless, those who use or inject drugs, and people living in poor sanitary conditions.

Why is Hepatitis A a Concern for Travelers?

Hepatitis A is a vaccine-preventable infection of the liver caused by the Hepatovirus. It spreads primarily through contaminated food or water, particularly in areas with inadequate sanitation. While Hepatitis A is often mild in healthy individuals, it can cause severe illness and even death in vulnerable groups. The impact of Hepatitis A is compounded in areas where health infrastructure is strained or where residents have limited access to healthcare.

The European Centre for Disease Prevention and Control (ECDC) has noted that the ongoing outbreak is predominantly affecting homeless populations, people who use drugs, and those living in communities with limited access to clean water and healthcare services. Despite the targeted groups, travelers, especially those visiting crowded urban centers like Prague, are at risk if they don’t take appropriate precautions.

How Can Travelers Protect Themselves?

For travelers visiting Prague, the best form of protection is to receive a Hepatitis A vaccination. Health experts recommend that unvaccinated individuals who are one year old or older, planning to visit Czechia, should receive the vaccine at least two weeks before traveling. This recommendation is endorsed by both the US Centers for Disease Control and Prevention (CDC) and the European Centre for Disease Prevention and Control (ECDC).

• Vaccination: Hepatitis A vaccination is highly effective in preventing the disease and is recommended for tourists heading to areas with outbreaks, like Czechia.
• Timing: It’s best to get the vaccination at least 2 weeks before traveling to ensure maximum protection.
• High-risk Groups: Unvaccinated travelers over 40 years old, those with chronic medical conditions, or individuals with weakened immune systems should receive both the initial vaccine dose and immune globulin at the same appointment.

The vaccination is widely available in health clinics and pharmacies across Europe and the United States, making it accessible to most travelers.

Where are the Outbreaks Occurring in Czechia?

The recent outbreak of Hepatitis A in Czechia has been concentrated in the following regions:

• Prague (436 cases)
• Central Bohemia (202 cases)
• Moravian-Silesian Region (118 cases)

These areas have seen the highest rates of infection, particularly in communities with poor sanitation. Prague, as the capital city, attracts a significant number of international tourists, making it essential for visitors to be aware of the Hepatitis A risk.

Health Experts’ Recommendations: What Should Tourists Do?

In light of the ongoing outbreak, health experts stress the importance of vaccination and the adoption of hygienic practices:

• Get vaccinated before traveling, particularly if you plan to visit Prague or other affected regions in Czechia.
• Wash hands frequently and avoid drinking unboiled water or eating food from unhygienic street vendors.
• Use bottled water for drinking and brushing teeth when possible.
• Avoid unpeeled fruits and vegetables that might have been contaminated.

Impact on Tourism and Business

The rise in Hepatitis A cases in Prague and the surrounding regions could have implications for tourism and local businesses. Tourists visiting Prague may be concerned about health risks, especially in the city’s crowded areas. However, with the proper vaccinations and safety measures, the risk can be minimized.

For local businesses, particularly those in the hospitality and tourism sectors, the health advisory may result in increased awareness and the need for better hygiene standards in their operations. This could also affect international travel to Czechia, particularly from countries like the US and UK, where Hepatitis A vaccinations are widely recommended for travelers.

What Tourists Need to Know

For tourists planning to visit Prague or nearby areas in Czechia, here are the key things to remember:

• Vaccination: Ensure you’re vaccinated against Hepatitis A before your trip.
• Hygiene: Be vigilant about hygiene and sanitation during your travels.
• Timing: Get vaccinated at least 2 weeks before your trip to ensure full protection.
• Health Advisory: Stay informed about local outbreaks by checking with health services like the CDC or ECDC for the latest information.

Conclusion: Stay Safe and Enjoy Your Visit to Prague

While Prague remains a beautiful and historically rich destination for tourists, the recent Hepatitis A outbreak serves as a reminder of the importance of travel health precautions. With the proper vaccinations, tourists can minimize their risk and enjoy all that this wonderful city has to offer. Whether you’re visiting for the stunning architecture, the vibrant cultural scene, or the delicious food, taking simple health precautions will ensure you stay safe during your trip.

Key Takeaways:

• Hepatitis A vaccinations are recommended for all travelers to Czechia, especially for Prague.
• The outbreak has primarily affected vulnerable populations, but tourists are still at risk.
• Vaccination should be done 2 weeks before travel to ensure full protection.
• Stay informed about local health advisories and practice basic hygiene to stay safe.

For more information on vaccinations and health tips, check with the CDC, ECDC, and local health authorities in Czechia.